Hyperbiotics PRO-15 Probiotic

60 Pearl tablets
Patented delivery provides 15 strains of bacteria to promote the optimal balance of gut bacteria. Tablets have 15X more survivability in stomach acid than capsules. Reduces digestive upset by gradually releasing over 8-10 hours.
Best For
Improved digestion, Enhanced immunity, Increased energy levels, Heightened nutrient absorption, Supports weight control [1-5]
What's in It More than 5 Billion
Strength
5/5
Results
5/5
Safety
5/5
Ingredients of Concern

None

Purity Tested: Passed tests for yeast, mold and pathogenic bacteria, including E. coli, Salmonella spp., and Staphylococcus aureus.

  • Non-GMO
  • Gluten-free
  • Dairy-free

    • Pros:
    • Advanced, patented time-release technology probiotic supplement with 15 strains that provide 5 billion CFUs per serving for improved overall health
    • Pearl tablets contain probiotics in a micro-pearl form that increases the survivability in stomach acid by 15 times in comparison to capsules
    • Probiotics are gradually released over an 8-10 hour period which reduces the digestive discomfort that some of the probiotic supplements cause
    • Pearls bypass stomach acid and the probiotics travel deep into the intestinal tract alive
    • Enhances digestion
    • Promotes better weight management
    • Heightens immune system function
    • Encourages optimal mood and energy levels
    • Sensitive-stomach friendly
    • Increased metabolism
    • Improved nutrient absorption
    • Enriched with prebiotics
    • Vegetarian
    • Non-GMO
    • Free of yeast, dairy, soy, gluten, wheat, nuts, preservatives, sugar, artificial colors, and flavors

    Ingredients Concern:  None discovered

    Cons:  Supplement supplies 5 billion CFU at the time of manufacture, but a minimum of 1.5 Billion CFU can be expected at expiration, Probiotics may cause stomach discomfort in some people

    Co-founder Jamie Morea started Hyperbiotics after suffering from a terrible parasite infection. This caused her to thorougly research the importance of the gut and microbiome. She says "all health begins in the gut." Her company developed a patented technology that claims to have the most "survivable" strains of probiotics. Hyperbiotics cares about mother earth and actively participates in a carbon offset program that supports the Rimba Raya Biodiversity Reserve.
    Probiotics have been shown to improve allergic reactions and skin allergies in children [5], most of which are linked to the environmental exposure to allergens such as dust mites, dog or cat hair, and pollen. Furthermore, taking probiotics during pregnancy and adding probiotics to the diet of newborns helps target inherited skin problems [6]. In addition, the protection that probiotics provides for skin cells persists for years when the supplementation begins during infancy [7]. Probiotic supplementation is also associated with a reduced incidence of duration of diarrhea that is due to antibiotic use [8]. In addition, probiotics are frequently administered in hospital settings to target diarrhea that is caused by antibiotics [9]. In NICUs, probiotic supplementation is also used to boost health and target diarrhea in newborns [10]. Research shows that taking a minimum of 5 billion CFUs of probiotics daily promotes health in children, they can be taken safely on a regular basis, they do not typically interact with any medication, and they rarely cause adverse effects [5]. Research indicates that the daily serving of probiotics which supports optimal digestive and immune system function for adults is 10 billion CFUs [1, 5]. In addition, probiotics support healthy cholesterol, triglyceride, and liver fat levels, thereby promoting a healthier metabolism [18]. They also help improve the body's ability to degrade cholesterol which enhances weight control [18, 19].Prebiotics provide nutrients that enhance the growth and activity of the probiotics [4]. Probiotics help target digestive issues that are related to a damaged intestinal lining and the leakage of different substances in the gut [20].
    Improved digestion, Enhanced immunity, Increased energy levels, Heightened nutrient absorption, Supports weight control [1-5]
    Probiotics restore and maintain a healthy balance of good bacteria in the gut [1]. Probiotics also release enzymes that promote the digestion of food and enzymes that target bad bacteria as well as other harmful invaders, thereby improving overall digestive function [11]. In addition, they support the proper breakdown and transport of nutrients into the bloodstream and throughout the body [4]. By improving the digestive process, probiotics helps ensure that only low amounts of undigested food remain in the gut as undigested food often leads to stomach discomfort. In doing so, probiotics target bloating, constipation, gas, and diarrhea, especially when antibiotics are being taken [8].Probiotic supplementation is frequently recommended during and after antibiotic use because it restores healthy levels of good bacteria [9]. Probiotics boost natural antioxidant activity in the body and this takes some of the strain off of the immune system [12]. Therefore, immune system becomes stronger and more readily available to target foreign invaders due to added protection that is provided by probiotics. Probiotic supplementation during childhood enhances digestive health and immunity [5]. More specifically, young children who take probiotics have a less exaggerated immune response to allergens that may otherwise cause them to become hyper-allergic [13]. Furthermore, probiotics help disrupt an imbalance of pro-inflammatory and anti-inflammatory proteins [2]. In addition, probiotics play a protective role against common allergens due to their ability to improve the viscosity of the natural mucus lining in the airways that trap and excrete allergens [1]. This reduces reactions to allergens, including skin allergy reactions [5]. Probiotic supplementation in young children also disrupts harmful invaders from causing infections in the respiratory system because probiotics support increased levels of white blood cells and natural killer cells [14, 15]. Furthermore, probiotics release specific substances that have antimicrobial activity and this enhances immunity, respiratory health, and overall health [14, 16, 17]. Furthermore, clinical research indicates that probiotics support heart health and weight control by promoting the breakdown of cholesterol, triglycerides, and body fat in obese individuals and influencing the way cholesterol is absorbed in the gut [18, 19]. When an individual experiences a leaky gut it means that the protective lining of the stomach is broken down and inflammatory substances enter the blood stream where they can cause pain throughout the body. Probiotic supplementation helps promote the body's ability to repair and restore the protective lining and stomach function [20].

    Key Ingredients:  Proprietary Probiotic Blend - 5 Billion CFU: L. plantarum, L. fermentum, L. acidophilus, B. infantis, L. casei, B. longum, L. rhamnosus, B. lactis, L. reuteri, L. salivarius, L. paracasei, L. gasseri, B. bifidum, B. breve, S. thermophiles, Prebiotic Fructooligosaccharides (FOS)* - 25 mg


    All Ingredients:  Proprietary Probiotic Blend - 5 Billion CFU: L. plantarum, L. fermentum, L. acidophilus, B. infantis, L. casei, B. longum, L. rhamnosus, B. lactis, L. reuteri, L. salivarius, L. paracasei, L. gasseri, B. bifidum, B. breve, S. thermophiles, Prebiotic Fructooligosaccharides (FOS)* - 25 mg, Microcrystalline cellulose, hydroxypropyl methylcellulose, pectin*, stearic acid, sodium carbonate, guar gum, turmeric

    Daily Maintenance: Take 1 pearl tablet once per day. Intense Support: Take up to 3 pearl tablets per day.
    These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.
    1. Kechagia M, Basoulis D, et al. Health benefits of probiotics: a review. ISRN Nutr. 2013;2013:481651. 2. Doron S, Snydman DR, Gorbach SL. Lactobacillus GG: bacteriology and clinical applications. Gastroenterol Clin North Am. 2005;34(3):483-498. 3. Rask C, Adlerberth I, Berggren A, Ahren IL, Wold AE. Differential effect on cell-mediated immunity in human volunteers after intake of different lactobacilli. Clin Exp Immunol. 2013;172(2):321-332. 4. Sheridan PO, Bindels LB, et al. Can prebiotics and probiotics improve therapeutic outcomes for undernourished individuals? Gut Microbes. 2014; 5(1):74-82. 5. Kliglerr B, Cohrssen A. Probiotics. Am Fam Physician. 2008, 78(9):1073-1078. 6. Kalliomäki M, Salminen S, Arvilommi H, Kero P, Koskinen P, Isolauri E. Probiotics in primary disruption of atopic disease: a randomised placebo-controlled trial. Lancet. 2001;357(9262):1076-1079. 7. Kukkonen K, Savilahti E, Haahtela T, et al. Probiotics and prebiotic galacto-oligosaccharides in the disruption of allergic diseases: a randomized, double-blind, placebo-controlled trial. J Allergy Clin Immunol. 2007;119(1):192-198. 8. Hempel S, Newberry SJ, Maher AR, et al. Probiotics for the disruption and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. JAMA. 2012;307(18):1959-1969. 9. Ouwehand AC, DongLian C, Weijian X, et al. Probiotics reduce symptoms of antibiotic use in a hospital setting: a randomized dose response study. Vaccine. 2014;32(4):458-463. 10. Deshpande GC, Rao SC, Keil AD, Patole SK. Evidence-based guidelines for use of probiotics in preterm neonates. BMC Med. 2011;9:92. 11. Manzoni P, Mostert M, Leonessa ML, et al. Oral supplementation with Lactobacillus casei subspecies rhamnosus disrupts enteric colonization by Candida species in preterm neonates: a randomized study. Clin Infect Dis. 2006;42(12):1735-1742. 12. Gomes AC, de Sousa RG, Botelho PB, Gomes TL, Prada PO, Mota JF. The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double-blind, randomized trial. Obesity (Silver Spring, Md). 2017, 25(1):30-38. 13. Prescott SL, Dunstan JA, Hale J, et al. Clinical effects of probiotics are associated with increased interferon-gamma responses in very young children with atopic dermatitis. Clin Exp Allergy. 2005, 35(12):1557-1564. 14. Wang Y, Li X, et al. Probiotics for disruption and treatment of respiratory tract infections in children: A systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore). 2016;95(31):e4509. 15. Guillemard E, Tanguy J, Flavigny A, et al. Effects of consumption of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 on common respiratory and gastrointestinal infections in shift workers in a randomized controlled trial. J Am Coll Nutr 2010; 29:455-468. 16. Fooks LJ, Gibson GR. Probiotics as modulators of the gut flora. Br J Nutr. 2002;88 suppl 1:S39-S49. 17. Szajewska H, Konarska Z, Kolodziej M. Probiotic bacterial and fungal strains: claims with evidence. Dig Dis. 2016;34:251-259. 18. Costabile A, Buttarazzi I, Kolida S, et al. An in vivo assessment of the cholesterol-lowering efficacy of Lactobacillus plantarum ECGC 13110402 in normal to mildly hypercholesterolaemic adults. PloS one. 2017, 12(12):e0187964. 19. Famouri F, Shariat Z, Hashemipour M, Keikha M, Kelishadi R. Effects of Probiotics on Nonalcoholic Fatty Liver Disease in Obese Children and Adolescents. J Pediatr Gastroenterol Nutr. 2017, 64(3):413-417. 20. Gorbach SL. Probiotics and gastrointestinal health. Am J Gastroenterol 2000;95:S2-S4.
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