Pure Encapsulations - Calcium Magnesium (Citrate/Malate)

180 Capsules
Made in
Premium grade, hypoallergenic calcium supplement with magnesium for improved overall well-being. This highly absorbable formula was developed based on research which shows that calcium and magnesium work together to enhance cardiovascular function, bone health, and the metabolism of lipids (fats).
Best For
Those with bone issues /malabsorption & metabolism issues with calcium[8]; Enhanced immune system, heart, teeth, bone, and muscle health [1-7]
Ingredients of Concern


  • Vegetarian
  • Non-GMO
  • Gluten-free
  • Dairy-free
  • Soy-free
  • Nut-free

    • Pros:
    • Highly absorbable, hypoallergenic, and premium quality calcium supplement with magnesium for enhanced health
    • Supports bone health, cardiovascular function, and lipid metabolism
    • Pure, research-based ingredients
    • Facilitates the transfer of calcium into bones, muscles, and teeth
    • Targets plaque buildup in the arteries
    • Promotes muscle relaxation and contraction
    • Enhances energy production
    • Free from wheat, gluten, egg, peanuts, magnesium stearate, hydrogenated fat, artificial sweeteners, GMOs, and colors

    Ingredients Concern: None discovered


    Individuals who are pregnant or lactating, have any health condition, or are taking any medication, should consult a health professional before use

    Will have to take several pills to get to a high dosage per day (however this is a bioavailable form which has been shown to be more bioavailable than calcium carbonate, especially for individuals with low stomach acidity. Calcium citrate and the other calcium chelates that are used take up considerable volume, resulting in a maximum capsule capacity of 150 mg elemental calcium Noet that they also do not use tablets, which contain excipients, fillers, shellacs, artificial preservatives, etc, and thus cannot compress this powder to provide a higher dosage per serving.

    Pure Encapsulations is a trusted brand known for high quality supplements produced in NSF-GMP facilities in Massachussets which exceed the standards of the United States Pharmacopeia (USP). The Pure Encapsulations brand is known for meeting label claims and having a high level of quality assurance, but tend to be more expensive than other supplements that also meet label claims. Many doctors endorse their products. Their manufacturing process is so good that they welcome you to visit their plant and see how their products are made. Pure Encapsulations also ensures that their suppliers provide premium raw ingredients. All of their products are free from wheat, gluten, egg, peanuts, coatings, shellacs, GMOs, magnesium stearate, trans fat and hydrogenated oils, artificial colors and flavors, fillers and preservatives. This is really great for those that have allergies. They base a lot of their formulas on research.

    Magnesium heightens the activity of vitamin D3 and in doing so, enhances calcium transportation throughout the body, especially the bones, teeth, and muscles [1-4]. The combination of these two minerals supports processes such as energy production, nerve signal transmission, the development and growth of strong teeth and bones, proper muscle contraction and relaxation, optimal hormone and enzyme activity, health blood circulation and blood clotting; enhanced wound healing, among others [1-4].

    Based on peer reviewed studies and science, it is recommended to maintain calcium intake from 500-1000 mg day for older individuals at risk of osteoporosis, but there seems to be little need for calcium supplements except in individuals with major malabsorption problems or substantial abnormalities of calcium metabolism. Therefore, it is important to consult with a doctor before taking calcium. [8].

    Research indicates that widespread use of calcium supplements in individuals without a specific bone issue is not helpful, and may cause harm. Also, vitamin D supplements should be reserved for those with vitamin D deficiency or risk factors, principally low sunlight exposure or dark skin and not living in a sunny environment. These recommendations are consistent with those of the United States Preventive Services Task Force, which also does not support the use of either calcium or vitamin D supplements in otherwise healthy adults that live in communuties. The position of the International Osteoporosis Foundation is similar in that supplementation with calcium alone for fracture reduction is not supported by the literature but that calcium supplementation, with concomitant vitamin D supplementation, is supported for patients at high risk of calcium and vitamin D insufficiency [9].

    Those with bone issues /malabsorption & metabolism issues with calcium[8]; Enhanced immune system, heart, teeth, bone, and muscle health [1-7]
    Magnesium promotes the transfer of calcium into bones by accelerating the activity of vitamin D3 [1]. It also plays a role in the formation of hard tooth enamel that resists acid-induced tooth decay [2]. Without magnesium, calcium cannot be properly transported to the bones and teeth, and would instead begin to accumulate in organs such as the kidneys or liver [1, 2]. In addition, magnesium promotes muscle contraction and relaxation [3]. Low levels of magnesium are associated with electrolyte disorders and may contribute to the development of muscle fatigue, cramps, and spasms [3]. Furthermore, magnesium supports heart health by influencing electrical signals that regulate the heartbeat [4]. In addition, magnesium helps lowers the accumulation of fatty/lipid (plaque) build up in the arteries and it improves blood flow, which supports optimal blood pressure [4]. Magnesium's ability to raise Vitamin D3 levels leads to the vitamin D-induced increase of calcium and phosphorus as theses nutrients work together to facilitate the growth of new bone [5-7]. More specifically, vitamin D3 ensures the body properly transports calcium into the bones where it is used to build layers of strong bone tissue; the absence of adequate calcium levels in the bones causes them to become brittle and prone to fracture [7].

    Key Ingredients:  Each serving size (3 capsules) contains: Calcium (as calcium citrate/malate) 225 mg, Magnesium (as magnesium citrate/malate) 225 mg

    All Ingredients:  Calcium (as calcium citrate/malate), Magnesium (as magnesium citrate/malate), vegetarian capsule (cellulose, water), ascorbyl palmitate

    As a dietary supplement, take 3 capsules, 1-2 times daily, with or between meals. This product is shipped with a desiccant. In order to maintain product freshness, customers are encouraged to leave the desiccant in the package until contents are consumed.

    These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.

    1. Castiglioni S, Cazzaniga A, Albisetti W, Maier JA. Magnesium and osteoporosis: current state of knowledge and future research directions. Nutrients. 2013;5(8):3022-33. 2. Klimuszko E, Orywal K, et al. Evaluation of calcium and magnesium contents in tooth enamel without any pathological changes: in vitro preliminary study. Odontology. 2018;106(4):369-376. 3. Dominguez LJ, Barbagallo M, et al. Magnesium and muscle performance in older persons: the InCHIANTI study. Am J Clin Nutr. 2006;84(2):419-26. 4. Douban S, Brodsky MA, Whang DD, Whang R. Significance of magnesium in congestive heart failure. Am Heart J 1996;132:664-71. 5. Armas LA, Hollis BW, Heaney RP. Vitamin D2 is much less effective than vitamin D3 in humans. J Clin Endocrinol Metab 2004;89:5387-91. 6. Wolpowitz D, Gilchrest BA. The vitamin D questions: how much do you need and how should you get it? J Am Acad Dermatol. 2006;54(2):301-17 7. Cranney A, Horsley T, O'Donnell S, et al. Effectiveness and safety of vitamin D in relation to bone health. Evid Rep Technol Assess (Full Rep). 2007;(158):1-235. 8. Reid, I. R., S. M. Bristow, and M. J. Bolland. "Calcium supplements: benefits and risks." Journal of internal medicine 278.4 (2015): 354-368. 9. Reid, Ian R., and Mark J. Bolland. "Calcium and/or vitamin D supplementation for the prevention of fragility fractures: who needs it?." Nutrients 12.4 (2020): 1011.
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