Hyaluronic Acid and Vitamin C

Half of all the HA in your body is located in your skin. Like collagen, HA helps keep your skin strong and flexible. It is also important for keeping your skin hydrated by holding moisture in. As you age, your skin cells start producing less and less HA. When this happens, your skin loses its integrity and becomes less taut and flexible.² Supplementing with HA either orally or topically can help restore your skin and reduce signs of aging.

The anti-aging benefits of vitamin C, or ascorbic acid, are well known. Vitamin C has many important functions throughout the body and is a very effective antioxidant. It efficiently neutralizes reactive oxygen species that cause damage to cells and structural molecules in your body. Supplementation with vitamin C can reduce these harmful oxygen radicals and other molecular markers of aging. It can also improve skin elasticity and reduce wrinkles.²

For the maximum benefits for your skin, look for lotions, creams, or moisturizers that contain HA and vitamin C together.¹ Alternatively, you can use a vitamin C product and an HA product in order to get their compound effects.

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As an integral structural component, HA is important for wound-healing and rebuilding damaged tissues.³ It forms the fiber networks that holds cells and tissues together along with other structural molecules, such as collagen. Collagen and HA are especially abundant in tissues that need to be tough yet flexible, such as your skin, joints, and tendons. If you are injured, your body needs plenty of HA and collagen to close wounds, repair tendons, and heal joints.

Vitamin C is a coenzyme for collagen synthesis. This means that enzymes in your body need vitamin C in order to make new collagen proteins. Supplementing with vitamin C can increase collagen production in your body to facilitate healing. Topical vitamin C, which can be found in cosmetics like lotions and creams, can help your skin heal better.⁴ You can also take it orally to help with minor internal injuries, such as sprained joints.

Some recent studies have shown that vitamin C and HA are especially effective in promoting healing for skin and tendons, when used in combination.^{5, 6}

The powerful antioxidant properties of vitamin C make it good for reducing inflammation in the body. This is especially useful for diseases that involve high levels of inflammation, such as arthritis. In arthritis, constant inflammation causes swelling and tissue damage in affected joints. Reducing inflammation is essential for getting arthritis under control.

Vitamin C and HA have a synergistic effect on chondrocytes, the cells that form the cartilage in your joints. Together, they have an increased ability to reduce inflammation and damage to cartilage proteins.⁷ With their healing properties, the two nutrients together also help promote regeneration of joint tissues.