- Provides digestive and immune system support
- Designed specifically for kids with strong and large cell sized Saccharomyces boulardii lyo strain
- One of the only probiotic supplements with Saccharomyces boulardii lyo CNCM I-745
- Appropriate for children ages 2 months and up
- Individually packaged
- Tasty tutti-frutti flavor
- Contains the prebiotic (fructose) that nourishes probiotics
- Freeze-drying process protects the life of the probiotic cells
- No refrigeration needed
- Easy-to-use for those with busy schedules and children with active lifestyles
Ingredients Concern: None discovered
Cons: Contains lactose that may affect people who are highly intolerant or highly sensitive to lactose, Probiotics may cause stomach discomfort in some children including thirst or mild constipation, In very rare cases, may cause allergic reactions (e.g., skin rash), Cannot be used in the acute-care setting, especially in individuals with open arterial and venous access required (e.g., Vascath, Permcath, or AV fistula). Cannot be used for any individual with a central line or port or in the surroundings of any patient with a central line or port. Cannot be used for pre- or post- organ or bone marrow transplant patients and other patients considered severely immunocompromised or critically ill. Cannot be used if a person is allergic to any of the components (especially yeast).
Florastor is the only probiotic in North America to contain S. boulardii lyo CNCM I- 745.
Biocodex is a company with a belief that clinical studies can uncover more ways that Florastor can positively impact your microbiome.
In the early 1920s, Henri Boulard, a French agricultural engineer and microbiologist, traveled to Indochina in search of heat-resistant yeast and
he encountered a cholera outbreak. He happened to take note that locals were drinking a tea - made from lychee and mangosteen skins - to help with digestion.
Fascinated by the healing properties, Boulard did research and discovered the skins contained a unique yeast, which he later called Saccharomyces boulardii.
Boulard sold his patented strain to the French pharmaceutical company, Biocodex in 1953. Biocodex enhanced the strain's fermentation process to elevate it to pharmaceutical quality.
As the first probiotic in human medicine, S. boulardii lyo CNCM I-745 was the first yeast demonstrated to have probiotic properties. Since it's discovery, S. boulardii lyo CNCM I-745 has been researched in more than 600 clinical trials.
Probiotics help maintain the optimal balance of healthy intestinal bacteria and it targets stomach problems including diarrhea [2, 4, 5]. Probiotics helps break down undigested carbohydrates, sugars, and other nutrients, while boosting the levels of digestive enzymes [1, 6]. Supports the overall immune system by boosting the levels of anti-inflammatory proteins and immunoglobulins . Saccharomyces boulardii can withstand the harsh environment of the stomach to reach the intestines where they boost intestinal health . Probiotics continue to provide health benefits during antibiotic use and also target diarrhea linked to antibiotic use [7-9]. They can help prevent diarrhea from travelling and from antibiotic use. [11-12]
Promotes digestive balance [1, 2]; Supports Immune system health ; Helps prevent diarrhea caused by traveling or antibiotics [11-12]
Saccharomyces boulardii modulates immune system activity by stimulating the enhanced production of lgA and IL-10, and confers this activity better than other forms of probiotics . Similar to other probiotics, Saccharomyces boulardii supports a healthy digestive tract and keeps the intestines functioning well by restoring the optimal balance of good gut bacteria, and the digestive tract is the location where the majority (about 70%) of immunity is conferred [2, 3]. Healthy levels of good bacteria make it harder for bad bacteria to grow and this disrupts illness and infections . The larger cell size of Saccharomyces boulardii covers a wider surface area in the intestines, thereby providing optimal protection of the intestinal environment and enhanced immunity [2-4]. Furthermore, Saccharomyces boulardii enhances the activity of the lactase enzyme, which improves the body's ability to process lactose .
Saccharomyces boulardii continues to work during antibiotic use and targets diarrhea linked to antibiotic use; not all probiotics can be taken with antibiotics [7-9]. This strain has shown significant results in prevention of diarrhea from traveling and from antibiotic use. [11-12]
Key Ingredients: 250 mg Saccharomyces boulardii lyo; 471.9 mg Fructose; 32.5 mg Lactose
All Ingredients: 471.9 mg Fructose; 250 mg Saccharomyces boulardii lyo; 32.5 mg Lactose; Colloidal anhydrous silica; tutti-frutti flavor
Mix the contents of 1 packet with water, apple juice, or other noncarbonated drinks. For babies, add to warm formula. Florastor Kids can also be added to apple sauce and other soft baby foods. Take 1 packet in the morning and 1 packet in the evening.
These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.
1. Kechagia M, Basoulis D, et al. Health benefits of probiotics: a review. ISRN Nutr. 2013;2013:481651.
2. Swidsinski A, Loening-Baucke V, et al. Biostructure of fecal microbiota in healthy subjects and patients with chronic idiopathic diarrhea. Gastroenterology. 2008;135(2):568-79.
3. Martins FS, Silva AA, et al. Comparative study of Bifidobacterium animalis, Escherichia coli, Lactobacillus casei and Saccharomyces boulardii probiotic properties. Arch Microbiol. 2009;191(8):623-30.
4. Lesage G, Bussey H. Cell wall assembly in Saccharomyces cerevisiae. Microbiol Mol Biol Rev. 2006;70(2):317-343.
5. Buts JP, Bernasconi P, et al. Response of human and rat small intestinal mucosa to oral administration of Saccharomyces boulardii. Pediatr Res. 1986;20(2):192-6.
6. Sheridan PO, Bindels LB, et al. Can prebiotics and probiotics improve therapeutic outcomes for undernourished individuals? Gut Microbes. 2014; 5(1):74-82.
7. Hempel S, Newberry SJ, Maher AR, et al. Probiotics for the disruption and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. JAMA. 2012;307(18):1959-1969.
8. Klein SM, Elmer GW, et al. Recovery and elimination of the biotherapeutic agent, Saccharomyces boulardii, in healthy human volunteers. Pharm Res. 1993;10(11):1615-
9. Vandenplas Y, Brunser O, Szajewska H. Saccharomyces boulardii in childhood. Eur J Pediatr. 2009;168(3):253-65.
10. Kollaritsch H, Holst H, Grobara P, Wiedermann G. Prophylaxe der Reisediarrh√∂e mit Saccharomyces boulardii. Ergebnisse einer plazebokontrollierten Doppelblindstudie [Prevention of traveler's diarrhea with Saccharomyces boulardii. Results of a placebo controlled double-blind study]. Fortschr Med. 1993 Mar 30;111(9):152-6. German. PMID: 8486328.
11. Videlock EJ, Cremonini F. Meta-analysis: probiotics in antibiotic-associated diarrhoea. Aliment Pharmacol Ther. 2012 Jun;35(12):1355-69. doi: 10.1111/j.1365-2036.2012.05104.x. Epub 2012 Apr 24. PMID: 22531096.